research advances

• • Extremely salty

    Salt-loving archaea use small negative amino acids to survive hostile conditions.

  • Deducing function from small structural clues

    Find structural similarities without relying on fold classification by using the MarkUs server.

• • Urea transporter

    The structure of a bacterial homolog of the mammalian urea transporter reveals a highly specific, channel-like transport mechanism.
    
    

  • Tips for crystallizing membrane proteins in lipidic mesophases

    Advice on this useful technique for crystallizing integral membrane proteins.

  • more this month

• featured molecule

  • Sugarcoating the surface: yeast Alg13

    Many proteins in our cells are decorated with carbohydrate chains, which make the proteins more stable and assist with their function. Using NMR, PSI researchers now understand how this enzyme builds these essential carbohydrates.

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• news

  • SG in the spotlight
  • New year, new science
  • Shorter NIH grant form launches
  • Fraud rocks protein community
  • Whatever happened to ...?

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• research library

  • Crystal Structure of the APOBEC3G Catalytic Domain Reveals Potential Oligomerization Interfaces
  • Crystal structure of DNA-PKcs reveals a large open-ring cradle comprised of HEAT repeats

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• events

  • Biophysical Society 54th Annual Meeting February 20 - February 24, 2010
    San Francisco (California), USA
  • 2010 PSI Enabling Technologies Workshop April 19 - March 21, 2010
    Bethesda (Maryland), USA

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