research advances

• • Proofreading RNA

    The structure of RNA polymerase II caught in the 'backtracked' state reveals how it ensures faithful transcription.
    
    

  • GFP to the rescue

    Modified 'superfolder' green fluorescent protein can quickly establish whether a protein is soluble.

• • Bacterial signaling puzzle

    The structure of the phosphodiesterase YkuI reveals how it binds cyclic di-GMP and might explain its activation.

  • Easy modeling

    Working on a protein with no known structure? Try the Phyre server for simple-to-interpret protein models.

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• featured molecule

  • Lysostaphin

    Drug-resistant strains are continually emerging. The structure of lysostaphin reveals the atomic details of a magic bullet against Staphylococcus aureus infections.

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• news

  • PSI in the Spotlight
  • Californian universities caught in budget hell
  • UK science pulled back to business
  • Open-access publishing gains another convert

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• research library

  • A general protocol for the crystallization of membrane proteins for X-ray structural investigation
  • Insights into substrate stabilization from snapshots of the peptidyl transferase center of the intact 70S ribosome

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• events

  • American Crystallographic Association (ACA) Annual Meeting July 25, 2009 - July 30, 2009
    Toronto (Ontario), Canada
  • 23rd Annual Symposium of The Protein Society July 25, 2009 - July 29, 2009
    Boston (Massachusetts), USA

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