news
December 2008 news
PSI in the Spotlight: December 2008
PSI-SGKB [doi:10.1038/nw_psisgkb.2008.15]
An easy way to nominate protein targets to the PSI centers
The PSI has created a centralized system that allows investigators to submit target suggestions to the 10 PSI structural genomics centers. These proposals are evaluated for feasibility and consistency with the overall PSI goals. Collectively, the four large-scale production centers are currently pursuing structural studies of over 1,400 community-nominated targets. The six PSI specialized centers, which focus on various structure-determination bottlenecks, also consider target nominations.
Submit target proposals from the PSI SGKB homepage.
Through the PSI SGKB homepage (see image), investigators can create an account that can store and submit multiple proposals. Proposals should include full protein sequence information, a brief outline describing why these targets should be studied, and a synopsis of previous work performed on these targets. Preference is given to novel targets with less than 30% identity to any other structure deposited in the PDB. Experimental method recommendations (X-ray or NMR) and specific PSI center suggestions (large-scale production or specialized) are encouraged. Upon submission, the proposal will be considered by a review committee within 30 days, and notifications will be forwarded to the investigator's primary e-mail address.
Detailed target proposal guidelines are available at http://kb.psi-structuralgenomics.org/KB/proposal-guidelines.html. For general inquiries about the Community Nominated Targets program, please contact Dr Ward W. Smith at Email: smithwar@nigms.nih.gov.
Explore the PSI SGKB at upcoming conferences
Would you like to know more about the PSI SGKB and the information that it provides?
Posters and demonstrations of the PSI SGKB and its related resources will be presented at these conferences:
- Keystone Symposia: Omics meets Cell Biology
Breckenridge, Colorado, USA
January 25 – 30, 2009 - US Human Proteome Organization Annual Meeting
San Diego, California, USA
February 22 – 25, 2009 - 53rd Annual Biophysical Society Meeting
Boston, Massachusetts, USA
February 28 – March 4, 2009 - 2009 PSI Workshop – Enabling Technologies for Structural Biology
Bethesda, Maryland, USA
March 4 – 6, 2009 - 2009 ASBMB/Experimental Biology Meeting
New Orleans, Louisiana, USA
April 18 – 22, 2009
Information about these and other biological conferences are available from the Events Calendar.
