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The collection includes articles from PSI research groups and the broader community
October 2008
Structure of the human voltage-dependent anion channel
Bayrhuber M., Meins T., Habeck M., Becker S., Giller K. et al.
Proceedings of the National Academy of Sciences 105, 15370 - 15375 (2008)
Crystal structure of an extensively simplified variant of bovine pancreatic trypsin inhibitor in which over one-third of the residues are alanines
Islam M., Sohya S., Noguchi K., Yohda M. and Kuroda Y.
Proceedings of the National Academy of Sciences 105, 15334 - 15339 (2008)
Large-scale evaluation of protein reductive methylation for improving protein crystallization.
Kim Y., Quartey P., Li H., Volkart L., Hatzos C. et al.
Nature Methods 5, 853 - 854 (2008)
Structural basis for RNA recognition by a type II poly(A)-binding protein
Song J., McGivern J., Nichols K., Markley J. and Sheets M.
Proceedings of the National Academy of Sciences 105, 15317 - 15322 (2008)
Structure and DNA binding of alkylation response protein AidB
Bowles T., Metz A., O'Quin J., Wawrzak Z. and Eichman B.
Proceedings of the National Academy of Sciences 105, 15299 - 15304 (2008)
Imaging of transient structures using nanosecond in situ TEM
Kim J., Lagrange T., Reed B., Taheri M., Armstrong M. et al.
Science 321, 1472 - 1475 (2008)
Activation of tyrosine kinases by mutation of the gatekeeper threonine
Azam M., Seeliger M., Gray N., Kuriyan J. and Daley G.
Nature Structural & Molecular Biology 15, 1109 - 1118 (2008)
Crystal structures of the SAM-III/SMK riboswitch reveal the SAM-dependent translation inhibition mechanism
Lu C., Smith A., Fuchs R., Ding F., Rajashankar K. et al.
Nature Structural & Molecular Biology 15, 1076 - 1083 (2008)
Plasticity of the PAS domain and a potential role for signal transduction in the histidine kinase DcuS
Etzkorn M., Kneuper H., Dunnwald P., Vijayan V., Kramer J. et al.
Nature Structural & Molecular Biology 15, 1031 - 1039 (2008)
The postfusion structure of baculovirus gp64 supports a unified view of viral fusion machines
Kadlec J., Loureiro S., Abrescia N., Stuart D. and Jones I.
Nature Structural & Molecular Biology 15, 1024 - 1030 (2008)
Tracking the structural dynamics of proteins in solution using time-resolved wide-angle X-ray scattering
Cammarata M., Levantino M., Schotte F., Anfinrud P., Ewald F. et al.
Nature Methods 5, 881 - 886 (2008)
A sodium-mediated structural switch that controls the sensitivity of Kir channels to PtdIns(4,5)P2
Rosenhouse-Dantsker A., Sui J., Zhao Q., Rusinova R., Rodriguez-Menchaca A. et al.
Nature Chemical Biology 4, 624 - 631 (2008)
Structural insights into the evolutionary paths of oxylipin biosynthetic enzymes
Lee D., Nioche P., Hamberg M. and Raman C.
Nature 455, 363 - 368 (2008)
Structural basis for specific cleavage of Lys 63-linked polyubiquitin chains
Sato Y., Yoshikawa A., Yamagata A., Mimura H., Yamashita M. et al.
Nature 455, 358 - 362 (2008)
Crystal structure of opsin in its G-protein-interacting conformation
Scheerer P., Park J., Hildebrand P., Kim Y., Krausz N. et al.
Nature 455, 497 - 502 (2008)
Structure of the Tribolium castaneum telomerase catalytic subunit TERT
Gillis A., Schuller A. and Skordalakes E.
Nature 455, 633 - 637 (2008)
An idea whose time has come.
Banci L., Baumeister W., Heinemann U., Schneider G., Silman I. et al.
Genome Biology 8, (2007)
Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Antonysamy S., Aubol B., Blaney J., Browner M., Giannetti A. et al.
Bioorganic & Medicinal Chemistry Letters 18, 2990 - 2995 (2008)
Recent avian H5N1 viruses exhibit increased propensity for acquiring human receptor specificity
Stevens J., Blixt O., Chen L., Donis R., Paulson J. et al.
Journal of Molecular Biology 381, 1382 - 1394 (2008)
X-ray structure of a soluble Rieske-type ferredoxin from Mus musculus.
Levin E., Elsen N., Seder K., McCoy J., Fox B. et al.
Acta Crystallographica D 64, 933 - 940 (2008)
Shotgun crystallization strategy for structural genomics II
Page R., Deacon A., Lesley S. and Stevens R.
Journal of Structural and Functional Genomics 6, 209 - 217 (2005)
Data management in structural genomics
Haquin S., Oeuillet E., Pajon A., Harris M., Jones A. et al.
Methods in Molecular Biology 426, 49 - 79 (2008)
Structural basis for suppression of a host antiviral response by influenza A virus.
Das K., Ma L., Xiao R., Radvansky B., Aramini J. et al.
Proceedings of the National Academy of Sciences 105, 13093 - 13098 (2008)
Structures of open (R) and close (T) states of prephenate dehydratase (PDT)--implication of allosteric regulation by L-phenylalanine.
Tan K., Li H., Zhang R., Gu M., Clancy S. et al.
Journal of Structural Bology 162, 94 - 107 (2008)
Towards rationalization of crystallization screening for small- to medium-sized academic laboratories
Newman J., Egan D., Walter T., Meged R., Berry I. et al.
Acta Crystallographica D 61, 1426 - 1431 (2005)
Structure and mechanism of the rebeccamycin sugar 4'-O-methyltransferase RebM.
Singh S., McCoy J., Zhang C., Bingman C., Phillips J.G. et al.
The Journal of Biological Chemistry 283, 22628 - 22636 (2008)
Structure-guided inhibitor design for human FAAH by interspecies active site conversion.
Mileni M., Johnson D., Wang Z., Everdeen D., Liimatta M. et al.
Proceedings of the National Academy of Sciences 105, 12820 - 12824 (2008)
TOPS++FATCAT
Veeramalai M., Ye Y. and Godzik A.
BMC Bioinformatics 9, (2008)
Reactivation of methionine synthase from Thermotoga maritima (TM0268) requires the downstream gene product TM0269.
Huang S., Romanchuk G., Pattridge K., Lesley S., Wilson I. et al.
Protein Science 16, 1588 - 1595 (2007)
Proteomics analysis unravels the functional repertoire of coronavirus nonstructural protein 3
Neuman B., Joseph J., Saikatendu K., Serrano P., Chatterjee A. et al.
Journal of Virology 82, 5279 - 5294 (2008)
Problem Solved* (*sort of)
Service R.
Science 321, 784 - 786 (2008)
Novel genes dramatically alter regulatory network topology in amphioxus
Zhang Q., Zmasek C., Dishaw L., Mueller M., Ye Y. et al.
Genome Biology 9, (2008)
An idea whose time has gone
Petsko G.
Genome Biol 8, (2007)
High throughput protein production and crystallization at NYSGXRC
Sauder M., Rutter M., Bain K., Rooney I., Gheyi T. et al.
Methods in Molecular Biology 426, 561 - 575 (2008)
Growth of novel protein structural data
Levitt M.
Proceedings of the National Academy of Sciences 104, 3183 - 3188 (2007)
GraFix
Kastner B., Fischer N., Golas M., Sander B., Dube P. et al.
Nature Methods 5, 53 - 55 (2008)
Functional insights from structural genomics
Forouhar F., Kuzin A., Seetharaman J., Lee I., Zhou W. et al.
Journal of Structural and Functional Genomics 8, (2007)
Detection of operons
Yan Y. and Moult J.
Proteins Structure Function and Bioinformatics 64, (2006)
Deciphering RNA structural diversity and systematic phylogeny from microbial metagenomes
Zhu Y., Pulukkunat D. and Li Y.
Nucleic Acids Research 35, (2007)
De novo computational design of retro-aldol enzymes
Jiang L., Althoff E., Clemente F., Doyle L., Röthlisberger D. et al.
Science 319, 1387 - 1391 (2008)
Crystal structure of homoserine O-succinyltransferase from Bacillus cereus at 2.4 A resolution
Zubieta C., Krishna S., McMullan D., Miller M., Abdubek P. et al.
Proteins 68, 999 - 1005 (2007)
Structural insights into NEDD8 activation of cullin-RING ligases
Duda D., Borg L., Scott D., Hunt H., Hammel M. et al.
Cell 134, 995 - 1006 (2008)
Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation.
Guo Z., Wu Y., Das D., Delon C., Cramer J. et al.
The EMBO Journal 27, 2444 - 2456 (2008)
Accurate NMR structures through minimization of an extended hybrid energy.
Nilges M., Bernard A., Bardiaux B., Malliavin T., Habeck M. et al.
Structure 16, 1305 - 1312 (2008)
Integration of small-angle X-ray scattering data into structural modeling of proteins and their assemblies
Förster F., Webb B., Krukenberg K., Tsuruta H., Agard D. et al.
Journal of Molecular Biology 382, 1089 - 1106 (2008)
Use of experimental crystallographic phases to examine the hydration of polar and nonpolar cavities in T4 lysozyme
Liu L., Quillin M. and Matthews B.
Proceedings of the National Academy of Sciences 105, 14406 - 14411 (2008)
Structures of BmrR-Drug Complexes Reveal a Rigid Multidrug Binding Pocket and Transcription Activation through Tyrosine Expulsion
Newberry K., Huffman J., Miller M., Vazquez-Laslop N., Neyfakh A. et al.
Journal of Biological Chemistry 283, 26795 - 26804 (2008)
Tuning Escherichia coli for membrane protein overexpression
Wagner S., Klepsch M., Schlegel S., Appel A., Draheim R. et al.
Proceedings of the National Academy of Sciences 105, 14371 - 14376 (2008)
Crystal structure of a self-assembling lipopeptide detergent at 1.20 A.
Ho D., Pomroy N., Cuesta-Seijo J. and Privé G.
Proceedings of the National Academy of Sciences 105, 12861 - 12866 (2008)
Structure of the 30S translation initiation complex
Simonetti A., Marzi S., Myasnikov A., Fabbretti A., Yusupov M. et al.
Nature 455, 416 - 420 (2008)
Structural coupling of SH2-kinase domains links Fes and Abl substrate recognition and kinase activation.
Filippakopoulos P., Kofler M., Hantschel O., Gish G., Grebien F. et al.
Cell 134, 793 - 803 (2008)
A double S shape provides the structural basis for the extraordinary binding specificity of Dscam isoforms.
Sawaya M., Wojtowicz W., Andre I., Qian B., Wu W. et al.
Cell 134, 1007 - 1018 (2008)