Neomycin Binding Site (PDB entry 2qbe and 2qbi
This Jmol image shows only a small section of the large ribosomal subunit (blue) along with ribosome recyclic factor (yellow) and the antibiotic neomycin (red). Two structures are shown--one that includes only RRF and the ribosome (PDB entry 2qbe), and one that includes the drug (PDB entry 2qbi). Use the buttons below to switch between the two structures, and notice that the drug distorts the RNA helix, pulling it away from RRF.
