New Web Portal to Advance Wide Range of Protein Studies
The Protein Structure Initiative (PSI), an effort supported by the National Institutes of Health (NIH), has launched an online resource that will enable scientists from across biomedical disciplines to easily access a wealth of information about proteins and to sp ...
Read more »
Welcome to the PSI SGKB Portal!
To get started please read our FAQ. Please send comments to
comments@psi-structuralgenomics.org
The Protein Structure Initiative Structural Genomics Knowledgebase (PSI SGKB) is designed to turn the products of the Protein Structure Initiative effort into knowledge that is important for understanding living systems and disease. The PSI SGKB is a key resource in the advancement of biology, biochemistry, functional genomics, pharmacology, bioinformatics, education and clinical medicine.
Use the following query form to search the PSI SGKB by one-letter code protein sequence, keyword or Protein Data Bank (PDB) identifier code. (Example Sequence Search)| News | Featured PSI Structures |
|---|---|
|
|
RNase TLiving cells are filled with RNases, but not highly destructive ones like our digestive RNase. Instead, our cellular RNases are specific and perform specialized tasks. Many of these choreograph the timely... Read more » |
| Functional Sleuth | Technical Highlight |
|
Functional Sleuth presents PSI structures lacking full functional annotation.
Explore these protein structures and add your input about the possible functions.
Begin exploring »
|
AutoStructure
AutoStructure is a protein structure determination tool that uses uninterpreted NOESY cross peaks together with structure calculation programs like XPLOR or DYANA to generate a 3D structure of the protein that is as close to the true structure as possible. AutoStructure uses an iterative bottom-up topology-constrained approach to analyze NOE peak lists. It first builds an initial fold ... Read more » |