New Web Portal to Advance Wide Range of Protein Studies
The Protein Structure Initiative (PSI), an effort supported by the National Institutes of Health (NIH), has launched an online resource that will enable scientists from across biomedical disciplines to easily access a wealth of information about proteins and to sp ...
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Welcome to the PSI SGKB Portal!
To get started please read our FAQ. Please send comments to
comments@psi-structuralgenomics.org
The Protein Structure Initiative Structural Genomics Knowledgebase (PSI SGKB) is designed to turn the products of the Protein Structure Initiative effort into knowledge that is important for understanding living systems and disease. The PSI SGKB is a key resource in the advancement of biology, biochemistry, functional genomics, pharmacology, bioinformatics, education and clinical medicine.
Use the following query form to search the PSI SGKB by one-letter code protein sequence, keyword or Protein Data Bank (PDB) identifier code. (Example Sequence Search)| News | Featured PSI Structures |
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RNase TLiving cells are filled with RNases, but not highly destructive ones like our digestive RNase. Instead, our cellular RNases are specific and perform specialized tasks. Many of these choreograph the timely... Read more » |
| Functional Sleuth | Technical Highlight |
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Functional Sleuth presents PSI structures lacking full functional annotation.
Explore these protein structures and add your input about the possible functions.
Begin exploring »
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High-pressure crystal cryocooling
The Cornell University component of the Hauptmann-Woodward-based Center for High Throughput Structural Biology has developed a high-pressure methodology to cool protein crystals to liquid nitrogen temperatures to reduce radiation damage. The high-pressure mythology eases or eliminates the need for additional penetrative cryoprotectants and results in mosaic spreads ... Read more » |